PO-0698: Clinical outcomes of 4D CBCT-guided stereotactic body radiotherapy for inoperable hepatocellular carcinomas

Poster: Clinical track: Gastrointestinal tumours (upper and lower GI)published_or_final_version3rd ESTRO Forum, Barcelona, Spain, 24-28 April 2015. In Radiotherapy & Oncology, 2015, v. 115, p. S342-S34

Disappearance of Ensemble-Averaged Josephson Current in Dirty SNS Junctions of d-wave Superconductors

We discuss the Josephson current in superconductor / dirty normal conductor / superconductor junctions, where the superconductors have $d_{x^2-y^2}$ pairing symmetry. The low-temperature behavior of the Josephson current depends on the orientation angle between the crystalline axis and the normal of the junction interface. We show that the ensemble-averaged Josephson current vanishes when the orientation angle is $\pi/4$ and the normal conductor is in the diffusive transport regime. The $d_{x^2-y^2}$-wave pairing symmetry is responsible for this fact.Comment: 8 pages, 5 figure

Time and Amplitude of Afterpulse Measured with a Large Size Photomultiplier Tube

We have studied the afterpulse of a hemispherical photomultiplier tube for an upcoming reactor neutrino experiment. The timing, the amplitude, and the rate of the afterpulse for a 10 inch photomultiplier tube were measured with a 400 MHz FADC up to 16 \ms time window after the initial signal generated by an LED light pulse. The time and amplitude correlation of the afterpulse shows several distinctive groups. We describe the dependencies of the afterpulse on the applied high voltage and the amplitude of the main light pulse. The present data could shed light upon the general mechanism of the afterpulse.Comment: 11 figure

Observational Constraints on Teleparallel Dark Energy

We use data from Type Ia Supernovae (SNIa), Baryon Acoustic Oscillations (BAO), and Cosmic Microwave Background (CMB) observations to constrain the recently proposed teleparallel dark energy scenario based on the teleparallel equivalent of General Relativity, in which one adds a canonical scalar field, allowing also for a nonminimal coupling with gravity. Using the power-law, the exponential and the inverse hyperbolic cosine potential ansatzes, we show that the scenario is compatible with observations. In particular, the data favor a nonminimal coupling, and although the scalar field is canonical the model can describe both the quintessence and phantom regimes.Comment: 19 pages, 6 figures, version accepted by JCA

Hall effect and resistivity in underdoped cuprates

The behaviour of the Hall ratio $R_{H}(T)$ as a function of temperature is one of the most intriguing normal state properties of cuprate superconductors. One feature of all the data is a maximum of $R_{H}(T)$ in the normal state that broadens and shifts to temperatures well above $T_c$ with decreasing doping. We show that a model of preformed pairs-bipolarons provides a selfconsistent quantitative description of $R_{H}(T)$ together with in-plane resistivity and uniform magnetic susceptibility for a wide range of doping.Comment: 4 pages, 2 figures, the model and fits were refine

Surveillance of emerging drugs of abuse in Hong Kong: Validation of an analytical tool

© 2015, Hong Kong Academy of Medicine Press. All rights reserved. Objective: To validate a locally developed chromatography-based method to monitor emerging drugs of abuse whilst performing regular drug testing in abusers. Design: Cross-sectional study. Setting: Eleven regional hospitals, seven social service units, and a tertiary level clinical toxicology laboratory in Hong Kong. Participants: A total of 972 drug abusers and high-risk individuals were recruited from acute, rehabilitation, and high-risk settings between 1 November 2011 and 31 July 2013. A subset of the participants was of South Asian ethnicity. In total, 2000 urine or hair specimens were collected. Main outcome measures: Proof of concept that surveillance of emerging drugs of abuse can be performed whilst conducting routine drug of abuse testing in patients. Results: The method was successfully applied to 2000 samples with three emerging drugs of abuse detected in five samples: PMMA (paramethoxymethamphetamine), TFMPP [1-(3-trifluoromethylphenyl)piperazine], and methcathinone. The method also detected conventional drugs of abuse, with codeine, methadone, heroin, methamphetamine, and ketamine being the most frequently detected drugs. Other findings included the observation that South Asians had significantly higher rates of using opiates such as heroin, methadone, and codeine; and that ketamine and cocaine had significantly higher detection rates in acute subjects compared with the rehabilitation population. Conclusions: This locally developed analytical method is a valid tool for simultaneous surveillance of emerging drugs of abuse and routine drug monitoring of patients at minimal additional cost and effort. Continued, proactive surveillance and early identification of emerging drugs will facilitate prompt clinical, social, and legislative management.Link_to_subscribed_fulltex

Lattice QCD Constraints on the Nuclear Equation of State

Based on the quasi-particle description of the QCD medium at finite temperature and density we formulate the phenomenological model for the equation of state that exhibits crossover or the first order deconfinement phase transition. The models are constructed in such a way to be thermodynamically consistent and to satisfy the properties of the ground state nuclear matter comply with constraints from intermediate heavy--ion collision data. Our equations of states show quite reasonable agreement with the recent lattice findings on temperature and baryon chemical potential dependence of relevant thermodynamical quantities in the parameter range covering both the hadronic and quark--gluon sectors. The model predictions on the isentropic trajectories in the phase diagram are shown to be consistent with the recent lattice results. Our nuclear equations of states are to be considered as an input to the dynamical models describing the production and the time evolution of a thermalized medium created in heavy ion collisions in a broad energy range from SIS up to LHC.Comment: 13 pages, 11 figure

Knowledge-based energy functions for computational studies of proteins

This chapter discusses theoretical framework and methods for developing knowledge-based potential functions essential for protein structure prediction, protein-protein interaction, and protein sequence design. We discuss in some details about the Miyazawa-Jernigan contact statistical potential, distance-dependent statistical potentials, as well as geometric statistical potentials. We also describe a geometric model for developing both linear and non-linear potential functions by optimization. Applications of knowledge-based potential functions in protein-decoy discrimination, in protein-protein interactions, and in protein design are then described. Several issues of knowledge-based potential functions are finally discussed.Comment: 57 pages, 6 figures. To be published in a book by Springe

Quantum Rotation of HCN and DCN in Helium-4

We present calculations of rotational absorption spectra of the molecules HCN and DCN in superfluid helium-4, using a combination of the Diffusion Monte Carlo method for ground state properties and an analytic many-body method (Correlated Basis Function theory) for the excited states. Our results agree with the experimentally determined effective moment of inertia which has been obtained from the $J=0\to 1$ spectral transition. The correlated basis function analysis shows that, unlike heavy rotors such as OCS, the J=2 and higher rotational excitations of HCN and DCN have high enough energy to strongly couple to rotons, leading to large shifts of the lines and accordingly to anomalous large spectroscopic distortion constants, to the emergence of roton-maxon bands, and to secondary peaks in the absorption spectra for J=2 and J=3.Comment: accepted by Phys. Rev. B; changes: included referee suggestions, removed typos, added 10 ref

Pairing in two-dimensional boson-fermion mixtures

The possibilities of pairing in two-dimensional boson-fermion mixtures are carefully analyzed. It is shown that the boson-induced attraction between two identical fermions dominates the p-wave pairing at low density. For a given fermion density, the pairing gap becomes maximal at a certain optimal boson concentration. The conditions for observing pairing in current experiments are discussedComment: 10 pages, 5 figs, revtex